The principal cytochrome P450 isoenzyme associated appears being CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. About 85% of an oral dose appears while in the urine in 24 hrs of administration, most given that the glucuronide conjugate, with little amounts of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity details.Within a frac… Read More